Gammaked Background

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

CIDP is the most commonly acquired demyelinating neuropathy. CIDP is an autoimmune disorder whereby autoantibodies attack and destroy the myelin sheath of the peripheral nerves.It can commonly present either as a continuously progressive affliction or, less often, as a recurrent disorder in which episodes (relapsing and remitting) in individual patients may be separated by months or years.

Since the etiology remains unknown, CIDP remains a syndrome with several variants, primarily defined by differences in clinical presentation. The classification is still debated, but virtually all neurologists define the disorder as being chronic (> 8 weeks progression), demyelinating and inflammatory or immune-mediated.

 

Reference1. Latov N. Diagnosis of CIDP. Neurology. 2002;59(12 suppl 6):S2-6.