Gammaked Background

Idiopathic Thrombocytopenic Purpura (ITP)

ITP, also known as primary immune thrombocytopenic purpura and autoimmune thrombocytopenic purpura. ITP is a clinical syndrome in which a decreased number of circulating platelets manifests as a bleeding tendency, easy bruising or extravasation of blood from capillaries into skin and mucous membranes.

ITP is primarily a disease of increased peripheral platelet destruction, with most patients having antibodies to specific platelet membrane glycoproteins. Acute ITP typically follows an acute infection and resolves within two months. Chronic ITP persists for more than 6 months with no specific cause.1

 

Reference: 1. Silverman MA. Idiopathic thrombocytopenic purpura. January 2007. www.emedicine.medscape.com. Accessed October 1, 2014.