Gammaked Background

Patients with Idiopathic Thrombocytpoenic Purpura


"Idiopathic" means that the cause is unknown. "Thrombocytopenic" means the blood doesn't have enough platelets. "Purpura" means excessive bruising.1 Platelets are fragments of cells found in the blood that your body needs to control bleeding. They seal minor cuts and wounds and form blood clots.1
If you have ITP, your immune system makes antibodies that destroy platelets.2 Having too few platelets can cause you to bruise easily and to bleed for a long time if you are injured. If the platelet count is very low, nose bleeding can occur as well as bleeding in the intestines.2


ITP can effect children and adults. In children, it is usually an acute, temporary condition that comes on fast, usually following an infection.In adults, ITP tends to be chronic, and is more common in women than in men.In children and in adults, diagnosing ITP can sometimes be difficult and may involve a complete blood count including platelets and bone marrow examination.2


Treatment for most people with ITP includes corticosteroids and immune globulin intravenous (IGIV).4 IGIV therapy, such as Gammaked, can quickly raise dangerously low platelet counts to control bleeding.5

References: 1. Dorland's Illustrated Medical Dictionary, 27th ed. Philadelphia, PA: W.B. Saunders; 1988. 2. Fauci AS, Braunwald E, Kasper DL, et al, eds. Harrison's Principles of Internal Medicine. 17th ed. New York, NY: McGraw-Hill; 2008. 3. Sandler SG, Bhanji R. Immune thrombocytopenic purpura. September 2012. eMedicine article. Accessed October 1, 2014. 4. Bussel JB, Eldor A, Kelton JG, et al, and the IGIV-C in ITP Study Group. IGIV-C, a novel intravenous immunoglobulin: evaluation of safety, efficacy, mechanisms of action, and impact on quality of life. Thromb Haemost. 2004;91:771-778. 5. GAMMAKED [package insert]. Fort Lee, NJ. Kedrion Biopharma Inc.; 2013.