Gammaked Background

Patients with Primary Immunodeficiency

WHAT IS PI?

Primary immunodeficiency (PI) is a genetic or inherited disease, which means it is a problem within your own immune system that you are born with.1,2 You can not catch it from someone else and you can not give it to someone else. When part of your immune system does not work the way it should, your body lacks the antibodies needed to fight off infection.

All kinds of people can have PI disease, from babies to grandparents. Bouts of pneumonia that occur within a short time period; persistent sinus, ear, or lung infections; or any recurring infections might indicate PI.1,2 Discuss your medical history with your doctor if you think you may have PI.

PI is not contagious and has absolutely no connection to AIDS (acquired immunodeficiency syndrome). A person with PI is not a threat to other people. However, other people carry and pass around germs that can cause illness in a person with PI.


PI CAN BE MANAGED:

IGIV therapy, such as Gammaked, is the primary therapy recommended by most doctors.2 IGIV therapy provides the antibodies you need to help your body fight off infection.2 Your doctor will work out a regular therapy schedule designed for your specific needs.


 

10 Warning Signs of Primary Immunodeficiency*

  1. Four or more new ear infections within 1 year
  2. Two or more serious sinus infections within 1 year
  3. Two or more months on antibiotics with little effect
  4. Two or more pneumonias within 1 year
  5. Failure of an infant to gain weight or grow normally
  6. Recurrent, deep skin or organ abscesses
  7. Persistent thrush in mouth or fungal infection on skin
  8. Need for intravenous antibiotics to clear infections
  9. Two or more deep-seated infections including septicemia
  10. A family history of primary immunodeficiency

*Developed by the Jeffrey Modell Foundation (JMF) 


References: 1. Fauci AS, Braunwald E, Kasper DL, et al, eds. Harrison's Principles of Internal Medicine. 17th ed. New York, NY: McGraw-Hill; 2008. 2. Lederman H, ed. Clinical focus on primary immune deficiencies: primary humoral immunodeficiency: optimizing IgG replacement therapy. Immune Deficiency Foundation. 2003:1-15.